Vibrational Spectroscopic Investigation of Blood Plasma and Serum by Drop Coating Deposition for Clinical Application

In recent decades, vibrational spectroscopic methods such as Raman and FT-IR spectroscopy are widely applied to investigate plasma and serum samples. These methods are combined with drop coating deposition techniques to pre-concentrate the biomolecules in the dried droplet to improve the detected vibrational signal. However, most often encountered challenge is the inhomogeneous redistribution of biomolecules due to the coffee-ring effect. In this study, the variation in biomolecule distribution within the dried-sample droplet has been investigated using Raman and FT-IR spectroscopy and fluorescence lifetime imaging method. The plasma-sample from healthy donors were investigated to show the spectral differences between the inner and outer-ring region of the dried-sample droplet. Further, the preferred location of deposition of the most abundant protein albumin in the blood during the drying process of the plasma has been illustrated by using deuterated albumin. Subsequently, two patients with different cardiac-related diseases were investigated exemplarily to illustrate the variation in the pattern of plasma and serum biomolecule distribution during the drying process and its impact on patient-stratification. The study shows that a uniform sampling position of the droplet, both at the inner and the outer ring, is necessary for thorough clinical characterization of the patient’s plasma and serum sample using vibrational spectroscopy.     

基于Prophet人工智能算法的网络潮汐效应预测研究

本文使用Prophet人工智能算法研究与预测移动通信网络“潮汐效应”现象，探索网络“潮汐效应”在优化网络资源配置实现网络降本增效的作用。Prophet人工智能算法是一种简单、有效，且易于实现的人工智能算法。通过facebook的人工智能开源框架fbprophet，研究4G网络PRB利用率等网络资源指标的“潮汐效应”，并预测这些网络资源指标在未来的变化趋势，用来指导当前4G网络减容、扩容和4/5G节电节能等，实现优化网络资源配置达到降本增效的目的。     

Inductive effect in Mn-doped ZnO nanoribon arrays grown on Ni foam: A promising key for boosted capacitive and high specific energy supercapacitors

Transition metal oxides have been explored in supercapacitor applications owing to their safety, low cost, high specific capacitance and high electrochemical activity. Among all transition metal oxides, zinc oxide based materials show remarkable response for designing the supercapacitors with high electrochemical activity. Here in, Mn doped ZnO (Zn_1-xMn_xO₃ with x = 0, 0.25, 0.50, 0.75 and 1) was synthesized by a facile hydrothermal method. Doping of Mn into the ZnO increased the surface area and decease the charge transfer resistance for the Zn_0.5Mn_0.5O₃. All the synthesized materials were characterized by x-ray diffraction (XRD), scanning electron microscopy SEM), BET, electrochemical tests and other various analytical techniques to confirm the structural, morphological, textural and suprcapacitive properties. The synthesized material Zn_0.5Mn_0.5O₃ having the porous nanoribons structure with BET surface area (2490 cm²/g). The electrochemical studies showed significantly enhanced response toward pseudocapacitive nature. The synthesized material exhibited the excellent specific capacitance (515F/g), specific energy (28.61 Wh/kg) and specific power (1000 W/kg) at current density of 2 mA/g. Such impressive and superior properties make the MnZnO₃ material as promising candidate for new generation supercapacitor applications.     

Touch sensor and photovoltaic characteristics of CuSbS2 thin films

Spin-coated chalcostibite CuSbS₂ thin films (≈500 nm thick) were fabricated and the influence of the drying temperature on the structural, morphological, optical and thermoelectric properties of the films was investigated. Crystalline phase-pure chalcostibite has been obtained for the films dried at 180 °C and 210 °C, while below 180 °C these films are partially amorphous. Surprisingly, at drying temperature of 240 °C, a Cu_xS secondary phase appeared. The increase of the drying temperature leads to the increase of the particle size and the decrease of the optical band gap, which is interesting for optoelectronic applications. The highest power factor value was achieved for the film dried at 210 °C, due to the inexistence of secondary phases, which allowed realizing a stable thermoelectric touch sensor with a V_signal/_noise of 5. In addition, this film was tested as a photovoltaic (PV) device and a power conversion efficiency (PCE) of 0.030% with an open-circuit voltage (V_OC) of 0.36 V, a short-circuit current density (J_SC) of 0.278 mAcm^?2 and a fill factor (FF) of 0.27 were obtained. Therefore, this work evidences a pathway toward developing bi-functional devices with simultaneously thermoelectric touch sensor and photovoltaic functions.     

Entrapping Ru nanoparticles into TiO2 nanotube: Insight into the confinement synergy on boosting pho-thermal CO2 methanation activity

CO₂ methanation is a significant route to decrease carbon emission as well as realize carbon neutrality and has gained considerable concerns from experts in the environment and energy field currently. Herein, highly dispersed ruthenium nanoparticles entrapped in TiO₂ nanotubes, labeled as Ru-in/TNT, were constructed and adopted for photo-thermal driven CO₂ methanation. The Ru nanoparticles confined in the nanotube exhibited an enhanced CO₂ methanation activity, especially under light irradiation. Multiple characterization techniques (XRD, XPS, UV–vis DRS, HRTEM, Raman, etc.) were conducted to reveal the effect of confinement synergy on photo-thermal catalytic performance. A boosted photo-generated electron-hole separation efficiency is achieved as a result of the confinement effect, yielding more hot electrons to accelerate methanation activity. This photo-assisted confinement synergy can be expected for constructing an efficient photo-thermal catalytic system.     

In Vivo Silencing of Genes Coding for dTip60 Chromatin Remodeling Complex Subunits Affects Polytene Chromosome Organization and Proper Development in Drosophila melanogaster

Chromatin organization is developmentally regulated by epigenetic changes mediated by histone-modifying enzymes and chromatin remodeling complexes. In Drosophila melanogaster, the Tip60 chromatin remodeling complex (dTip60) play roles in chromatin regulation, which are shared by evolutionarily-related complexes identified in animal and plants. Recently, it was found that most subunits previously assigned to the dTip60 complex are shared by two related complexes, DOM-A.C and DOM-B.C, defined by DOM-A and DOM-B isoforms, respectively. In this work, we combined classical genetics, cell biology, and reverse genetics approaches to further investigate the biological roles played during Drosophila melanogaster development by a number of subunits originally assigned to the dTip60 complex.     

气藏型储气库注气期试井分析探讨

针对气藏型储气库注采井注采过程中储层物性参数影响因素不明确、注采能力不对称的问题。基于相国寺储气库井下连续油管试井测试结果,提出储气库注气期“温降效应”、“变表皮效应”的概念,分析了储气库注采过程中温降效应、变表皮效应以及储层应力敏感对注采的影响。通过气藏型储气库注气期试井分析技术,研究各因素在试井曲线上的响应特征以及对试井解释参数的影响。结果表明:①相对于采气期试井测试,注气期测试得到的储层物性参数具有同样的参考价值;②储气库温降效应对于试井解释结果的影响可忽略不计,而在不同注采运行周期内,变表皮效应以及应力敏感效应影响差异较大;③编制储气库注采运行方案时应充分考虑变表皮效应与应力敏感的影响,在不同注采运行周期内开展试井测试获取准确的储层参数值。研究成果为储气库试井测试与解释提供了重要的研究依据和理论指导。     

认同度修正下的近相邻改进推荐算法研究

如何融合多方因素准确地为用户提供个性化产品一直是关注的热点问题，由此，一个新的近相邻改进算法融入了大众化认同度和个性化认同度，利于更加高效地挖掘隐藏信息。实验结果表明，相对于传统近相邻算法，认同度修正算法虽然查全率小幅度上下波动，但其他多个评价指标都得到极大提升，假正率和深度有所减少，查准率、[F1]值和提升度得以增加，并且，受试者特征曲线和提升曲线也都说明此修正算法具有更为显著的推荐效果。     

DCNN深度特征与交替方向乘子的相关滤波跟踪

针对采用相关滤波的判别式目标跟踪遇到的瓶颈问题：由于目标快速移动引起边界效应，使得相关滤波器在学习与更新过程中可能会引入错误，最终错误的累积将导致跟踪失败。在采集深度学习特征与样本相似性度量的基础上，提出一种引入交替方向乘子方法的改进相关滤波目标跟踪算法，选择DCNN深度特征有效地表征待跟踪目标的初始状态，通过在线分类过程中样本相似性比对与半监督学习，辅助解决相关滤波器在学习过程中存在的自学习问题。所提目标跟踪算法特别适合训练样本为持续获得的、同时存储空间较小的机器学习过程，提高目标在快速运动与部分遮挡等复杂情况下的跟踪成功率，针对VOT2016标准测试视频的实验表明：当目标面临快速运动时，对比CN、SAMF、STC算法，所提DA-CFT跟踪算法将跟踪成功率分别由60.4%～73.4%、67.2%～82.9%、80.9%～88.1%提升至85.6%～91.0%。     

Influences of the inner diameter of the solid shielding tube on the characteristics of the radio-frequency cold atmospheric plasma jet

Active control of the local environment of the cold atmospheric plasma (CAP) jet is of great importance in actual applications since the CAP operates in an open atmosphere with the inevitable entrainment of the surrounding cold air. In this paper, the solid shielding effects of the cylindrical quartz tubes with different inner diameters on the characteristics of the CAP jets driven by a radio-frequency (RF) power supply are studied experimentally. The experimental results show that the total length of the shielded plasma jet can be increased significantly by an appropriate combination of the quartz tube inner diameter and that of the plasma generator nozzle exit with other parameters being unchanged. This phenomenon may be qualitatively attributed to the loss of diffusion of the charged particles in the radial direction under different inner diameters of the quartz tubes. Compared with the plasma free jet, the plasma shielding jet is produced with optimized parameters including longer plasma jet length, higher concentrations of chemically reactive species, higher rotational, vibrational, and electron excitation temperatures when the inner diameters of the solid shielding tube and the generator nozzle exit are the same. A maximum plasma jet length of 52.0 cm is obtained in contrast to that of 5.0 cm of the plasma free jet in this study. The experimental results indicate that the solid shielding effect provides a new method for the active control of the local environment of the RF-CAP jet operating in an open atmosphere.